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Histone H4 H75E mutation attenuates global genomic and Rad26-independent transcription-coupled nucleotide excision repair

Nucleotide excision repair (NER) consists of global genomic NER (GG-NER) and transcription coupled NER (TC-NER) subpathways. In eukaryotic cells, genomic DNA is wrapped around histone octamers (an H3–H4 tetramer and two H2A–H2B dimers) to form nucleosomes, which are well known to profoundly inhibit...

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Foilsithe in:Nucleic Acids Res
Main Authors: Selvam, Kathiresan, Rahman, Sheikh Arafatur, Li, Shisheng
Formáid: Artigo
Teanga:Inglês
Foilsithe: Oxford University Press 2019
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6698655/
https://ncbi.nlm.nih.gov/pubmed/31114907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz453
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