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Histone H4 H75E mutation attenuates global genomic and Rad26-independent transcription-coupled nucleotide excision repair
Nucleotide excision repair (NER) consists of global genomic NER (GG-NER) and transcription coupled NER (TC-NER) subpathways. In eukaryotic cells, genomic DNA is wrapped around histone octamers (an H3–H4 tetramer and two H2A–H2B dimers) to form nucleosomes, which are well known to profoundly inhibit...
Enregistré dans:
| Publié dans: | Nucleic Acids Res |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6698655/ https://ncbi.nlm.nih.gov/pubmed/31114907 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz453 |
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