RNF216 is essential for spermatogenesis and male fertility

Ring finger protein 216 (RNF216) belongs to the RING family of E3 ubiquitin ligases that are involved in cellular protein degradation. Mutations in human Rnf216 gene have been identified in Gordon Holmes syndrome, which is defined by ataxia, dementia, and hypogonadotropism. However, the gene functio...

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Dades bibliogràfiques
Publicat a:Biol Reprod
Autors principals: Melnick, Ashley F, Gao, Yuen, Liu, Jiali, Ding, Deqiang, Predom, Alicia, Kelly, Catherine, Hess, Rex A, Chen, Chen
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2019
Matèries:
Letter to the Editor
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6698654/
https://ncbi.nlm.nih.gov/pubmed/30649198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/biolre/ioz006
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