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RNF216 is essential for spermatogenesis and male fertility

Ring finger protein 216 (RNF216) belongs to the RING family of E3 ubiquitin ligases that are involved in cellular protein degradation. Mutations in human Rnf216 gene have been identified in Gordon Holmes syndrome, which is defined by ataxia, dementia, and hypogonadotropism. However, the gene functio...

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Bibliografiske detaljer
Udgivet i:Biol Reprod
Main Authors: Melnick, Ashley F, Gao, Yuen, Liu, Jiali, Ding, Deqiang, Predom, Alicia, Kelly, Catherine, Hess, Rex A, Chen, Chen
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6698654/
https://ncbi.nlm.nih.gov/pubmed/30649198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/biolre/ioz006
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