RNF216 is essential for spermatogenesis and male fertility

Ring finger protein 216 (RNF216) belongs to the RING family of E3 ubiquitin ligases that are involved in cellular protein degradation. Mutations in human Rnf216 gene have been identified in Gordon Holmes syndrome, which is defined by ataxia, dementia, and hypogonadotropism. However, the gene functio...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Biol Reprod
Autori principali: Melnick, Ashley F, Gao, Yuen, Liu, Jiali, Ding, Deqiang, Predom, Alicia, Kelly, Catherine, Hess, Rex A, Chen, Chen
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2019
Soggetti:
Letter to the Editor
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6698654/
https://ncbi.nlm.nih.gov/pubmed/30649198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/biolre/ioz006
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