PNLDC1 is essential for piRNA 3′ end trimming and transposon silencing during spermatogenesis in mice

Piwi-interacting RNAs are small regulatory RNAs with key roles in transposon silencing and regulation of gametogenesis. The production of mature piwi-interacting RNAs requires a critical step of trimming piwi-interacting RNA intermediates to achieve optimally sized piwi-interacting RNAs. The poly(A)...

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Publicado en:Nat Commun
Main Authors: Ding, Deqiang, Liu, Jiali, Dong, Kunzhe, Midic, Uros, Hess, Rex A., Xie, Huirong, Demireva, Elena Y., Chen, Chen
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2017
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5635004/
https://ncbi.nlm.nih.gov/pubmed/29018194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-00854-4
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