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TDRD5 binds piRNA precursors and selectively enhances pachytene piRNA processing in mice

Pachytene piRNAs are the most abundant piRNAs in mammalian adult testes. They are generated from long precursor transcripts by the primary piRNA biogenesis pathway but the factors involved in pachytene piRNA precursors processing are poorly understood. Here we show that the Tudor domain-containing 5...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Ding, Deqiang, Liu, Jiali, Midic, Uros, Wu, Yingjie, Dong, Kunzhe, Melnick, Ashley, Latham, Keith E., Chen, Chen
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5760656/
https://ncbi.nlm.nih.gov/pubmed/29317670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-02622-w
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