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TDRD5 binds piRNA precursors and selectively enhances pachytene piRNA processing in mice

Pachytene piRNAs are the most abundant piRNAs in mammalian adult testes. They are generated from long precursor transcripts by the primary piRNA biogenesis pathway but the factors involved in pachytene piRNA precursors processing are poorly understood. Here we show that the Tudor domain-containing 5...

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Pubblicato in:Nat Commun
Autori principali: Ding, Deqiang, Liu, Jiali, Midic, Uros, Wu, Yingjie, Dong, Kunzhe, Melnick, Ashley, Latham, Keith E., Chen, Chen
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5760656/
https://ncbi.nlm.nih.gov/pubmed/29317670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-02622-w
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