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Cul4A is Essential for Spermatogenesis and Male Fertility

The mammalian Cul4 genes, Cul4A and Cul4B, encode the scaffold components of the cullin-based E3 ubiquitin ligases. The two Cul4 genes are functionally redundant. Recent study indicated that mice expressing a truncated CUL4A that fails to interact with its functional partner ROC1 exhibit no developm...

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Detalhes bibliográficos
Main Authors: Kopanja, Dragana, Roy, Nilotpal, Stoyanova, Tanya, Hess, Rex A., Bagchi, Srilata, Raychaudhuri, Pradip
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3065526/
https://ncbi.nlm.nih.gov/pubmed/21291880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2011.01.028
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