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Cul4A and DDB1 Associate with Skp2 To Target p27(Kip1) for Proteolysis Involving the COP9 Signalosome

DDB1, a subunit of the damaged-DNA binding protein DDB, has been shown to function also as an adaptor for Cul4A, a member of the cullin family of E3 ubiquitin ligase. The Cul4A-DDB1 complex remains associated with the COP9 signalosome, and that interaction is conserved from fission yeast to human. S...

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Autores principales: Bondar, Tanya, Kalinina, Anna, Khair, Lyne, Kopanja, Dragana, Nag, Alo, Bagchi, Srilata, Raychaudhuri, Pradip
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2006
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1430311/
https://ncbi.nlm.nih.gov/pubmed/16537899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.26.7.2531-2539.2006
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