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Proliferation Defects and Genome Instability in Cells Lacking Cul4A
The Cul4A gene, which encodes a core component of a cullin-based E3 ubiquitin ligase complex, is over-expressed in breast and hepatocellular cancers. In breast cancers, over-expression of Cul4A strongly correlates with poor prognosis. Also, Cul4A is required for early embryonic development. Early le...
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| Hoofdauteurs: | , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2009
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2705479/ https://ncbi.nlm.nih.gov/pubmed/19430492 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2009.86 |
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