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UvrD helicase activation by MutL involves rotation of its 2B subdomain

Escherichia coli UvrD is a superfamily 1 helicase/translocase that functions in DNA repair, replication, and recombination. Although a UvrD monomer can translocate along single-stranded DNA, self-assembly or interaction with an accessory protein is needed to activate its helicase activity in vitro....

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Ordabayev, Yerdos A., Nguyen, Binh, Kozlov, Alexander G., Jia, Haifeng, Lohman, Timothy M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6697780/
https://ncbi.nlm.nih.gov/pubmed/31363055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1905513116
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