IL-11 Induces Encephalitogenic Th17 Cells in Multiple Sclerosis and Experimental Autoimmune Encephalomyelitis

IL-11(+)CD4(+) cells accumulate in the cerebrospinal fluid of patients with early relapsing-remitting multiple sclerosis (MS) and in active brain MS lesions. Mouse studies have confirmed a causal role of IL-11 in the exacerbation of relapsing-remitting experimental autoimmune encephalomyelitis (RREA...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Zhang, Xin, Kiapour, Nazanin, Kapoor, Sahil, Khan, Tabish, Thamilarasan, Madhan, Tao, Yazhong, Cohen, Stephanie, Miller, Ryan, Sobel, Raymond A., Markovic-Plese, Silva
Formato: Artigo
Idioma:Inglês
Publicado em: AAI 2019
Assuntos:
Autoimmunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6697738/
https://ncbi.nlm.nih.gov/pubmed/31341075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1900311
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