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Th1, Th17 and Th9 effector cells induce experimental autoimmune encephalomyelitis with different pathological phenotypes
Experimental autoimmune encephalomyelitis (EAE) is a model of human multiple sclerosis (MS) induced by auto-reactive T helper cells that mediate tissue inflammation and demyelination in the CNS. Initially, IFN-γ-producing Th1 cells and, more recently, IL-17-producing Th17 cells with specificity for...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2921715/ https://ncbi.nlm.nih.gov/pubmed/19890056 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0901906 |
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