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Th1, Th17 and Th9 effector cells induce experimental autoimmune encephalomyelitis with different pathological phenotypes

Experimental autoimmune encephalomyelitis (EAE) is a model of human multiple sclerosis (MS) induced by auto-reactive T helper cells that mediate tissue inflammation and demyelination in the CNS. Initially, IFN-γ-producing Th1 cells and, more recently, IL-17-producing Th17 cells with specificity for...

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Autors principals: Jäger, Anneli, Dardalhon, Valérie, Sobel, Raymond A., Bettelli, Estelle, Kuchroo, Vijay K.
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2921715/
https://ncbi.nlm.nih.gov/pubmed/19890056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0901906
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