Nalaganje...
Generation of amine dehydrogenases with increased catalytic performance and substrate scope from ε-deaminating L-Lysine dehydrogenase
Amine dehydrogenases (AmDHs) catalyse the conversion of ketones into enantiomerically pure amines at the sole expense of ammonia and hydride source. Guided by structural information from computational models, we create AmDHs that can convert pharmaceutically relevant aromatic ketones with conversion...
Shranjeno v:
| izdano v: | Nat Commun |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group UK
2019
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6697735/ https://ncbi.nlm.nih.gov/pubmed/31420547 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11509-x |
| Oznake: |
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