Mechanistically detailed systems biology modeling of the HGF/Met pathway in hepatocellular carcinoma

Hepatocyte growth factor (HGF) signaling through its receptor Met has been implicated in hepatocellular carcinoma tumorigenesis and progression. Met interaction with integrins is shown to modulate the downstream signaling to Akt and ERK (extracellular-regulated kinase). In this study, we developed a...

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Detalhes bibliográficos
Publicado no:NPJ Syst Biol Appl
Main Authors: Jafarnejad, Mohammad, Sové, Richard J., Danilova, Ludmila, Mirando, Adam C., Zhang, Yu, Yarchoan, Mark, Tran, Phuoc T., Pandey, Niranjan B., Fertig, Elana J., Popel, Aleksander S.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6697704/
https://ncbi.nlm.nih.gov/pubmed/31452933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41540-019-0107-2
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