The Effects of Mitragynine and Morphine on Schedule-Controlled Responding and Antinociception in Rats

RATIONALE. Mitragyna speciosa (kratom) may hold promise as both an analgesic and treatment for opioid use disorder. Mitragynine, its primary alkaloid constituent, is an opioid receptor ligand. However, the extent to which the in vivo effects of mitragynine are mediated by opioid receptors, or whethe...

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Publicat a:Psychopharmacology (Berl)
Autors principals: Hiranita, Takato, Leon, Francisco, Felix, Jasmine S., Restrepo, Luis F., Reeves, Morgan E., Pennington, Anna E., Obeng, Samuel, Avery, Bonnie A., McCurdy, Christopher R., McMahon, Lance R., Wilkerson, Jenny L.
Format: Artigo
Idioma:Inglês
Publicat: 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6697625/
https://ncbi.nlm.nih.gov/pubmed/31098655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-019-05247-7
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