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The next generation BET inhibitor, PLX51107, delays melanoma growth in a CD8-mediated manner
Epigenetic agents such as bromodomain and extra terminal region inhibitors (BETi) slow tumor growth via tumor intrinsic alterations; however, their effects on anti-tumor immunity remain unclear. A recent advance is the development of next generation BETi that are potent and display a favorable half-...
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| Publicado no: | Pigment Cell Melanoma Res |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6697571/ https://ncbi.nlm.nih.gov/pubmed/31063649 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/pcmr.12788 |
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