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Overstretching Double-Stranded RNA, Double-Stranded DNA, and RNA-DNA Duplexes

Using single-molecule force measurements, we compare the overstretching transition of the four types of duplexes composed of DNA or RNA strands. Three of the four extremities of each double helix are attached to two microscopic beads, and a stretching force is applied with a dual-beam optical trappi...

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Bibliografiske detaljer
Udgivet i:Biophys J
Main Authors: Melkonyan, Lena, Bercy, Mathilde, Bizebard, Thierry, Bockelmann, Ulrich
Format: Artigo
Sprog:Inglês
Udgivet: The Biophysical Society 2019
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6697464/
https://ncbi.nlm.nih.gov/pubmed/31337545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2019.07.003
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