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GC-Content Dependence of Elastic and Overstretching Properties of DNA:RNA Hybrid Duplexes

DNA:RNA hybrid duplex plays important roles in various biological processes. Both its structural stability and interactions with proteins are highly sequence dependent. In this study, we utilize homebuilt optical tweezers to investigate how GC contents in the sequence influence the structural and me...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Yang, Dongni, Liu, Wenzhao, Deng, Xiangyu, Xie, Wei, Chen, Hu, Zhong, Zhensheng, Ma, Jie
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7451903/
https://ncbi.nlm.nih.gov/pubmed/32738216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2020.06.034
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