GC-Content Dependence of Elastic and Overstretching Properties of DNA:RNA Hybrid Duplexes

DNA:RNA hybrid duplex plays important roles in various biological processes. Both its structural stability and interactions with proteins are highly sequence dependent. In this study, we utilize homebuilt optical tweezers to investigate how GC contents in the sequence influence the structural and me...

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Veröffentlicht in:Biophys J
Hauptverfasser: Yang, Dongni, Liu, Wenzhao, Deng, Xiangyu, Xie, Wei, Chen, Hu, Zhong, Zhensheng, Ma, Jie
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Biophysical Society 2020
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7451903/
https://ncbi.nlm.nih.gov/pubmed/32738216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2020.06.034
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