GC-Content Dependence of Elastic and Overstretching Properties of DNA:RNA Hybrid Duplexes

DNA:RNA hybrid duplex plays important roles in various biological processes. Both its structural stability and interactions with proteins are highly sequence dependent. In this study, we utilize homebuilt optical tweezers to investigate how GC contents in the sequence influence the structural and me...

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Vydáno v:Biophys J
Hlavní autoři: Yang, Dongni, Liu, Wenzhao, Deng, Xiangyu, Xie, Wei, Chen, Hu, Zhong, Zhensheng, Ma, Jie
Médium: Artigo
Jazyk:Inglês
Vydáno: The Biophysical Society 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7451903/
https://ncbi.nlm.nih.gov/pubmed/32738216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2020.06.034
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