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Overstretching Double-Stranded RNA, Double-Stranded DNA, and RNA-DNA Duplexes

Using single-molecule force measurements, we compare the overstretching transition of the four types of duplexes composed of DNA or RNA strands. Three of the four extremities of each double helix are attached to two microscopic beads, and a stretching force is applied with a dual-beam optical trappi...

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Détails bibliographiques
Publié dans:Biophys J
Auteurs principaux: Melkonyan, Lena, Bercy, Mathilde, Bizebard, Thierry, Bockelmann, Ulrich
Format: Artigo
Langue:Inglês
Publié: The Biophysical Society 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6697464/
https://ncbi.nlm.nih.gov/pubmed/31337545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2019.07.003
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