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mTOR and Other Effector Kinase Signals that Impact T Cell Function and Activity

T cells play important roles in autoimmune diseases and cancers. Following the cloning of the T cell receptor (TCR), the race was on to map signaling proteins that contributed to T cell activation, downstream of the TCR as well as co-stimulatory molecules such as CD28. We term this “canonical TCR si...

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Détails bibliographiques
Publié dans:Immunol Rev
Auteurs principaux: Myers, Darienne R., Wheeler, Benjamin, Roose, Jeroen P.
Format: Artigo
Langue:Inglês
Publié: 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6697425/
https://ncbi.nlm.nih.gov/pubmed/31402496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imr.12796
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