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Peripheral PD-1+CD56+ T-cell frequencies correlate with outcome in stage IV melanoma under PD-1 blockade

Immune checkpoint blockade with anti-PD-1 antibodies is showing great promise for patients with metastatic melanoma and other malignancies, but despite good responses by some patients who achieve partial or complete regression, many others still do not respond. Here, we sought peripheral blood T-cel...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Bochem, Jonas, Zelba, Henning, Amaral, Teresa, Spreuer, Janine, Soffel, Daniel, Eigentler, Thomas, Wagner, Nikolaus Benjamin, Uslu, Ugur, Terheyden, Patrick, Meier, Friedegund, Garbe, Claus, Pawelec, Graham, Weide, Benjamin, Wistuba-Hamprecht, Kilian
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6697319/
https://ncbi.nlm.nih.gov/pubmed/31419253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0221301
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