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Peripheral PD-1+CD56+ T-cell frequencies correlate with outcome in stage IV melanoma under PD-1 blockade

Immune checkpoint blockade with anti-PD-1 antibodies is showing great promise for patients with metastatic melanoma and other malignancies, but despite good responses by some patients who achieve partial or complete regression, many others still do not respond. Here, we sought peripheral blood T-cel...

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Publicat a:PLoS One
Autors principals: Bochem, Jonas, Zelba, Henning, Amaral, Teresa, Spreuer, Janine, Soffel, Daniel, Eigentler, Thomas, Wagner, Nikolaus Benjamin, Uslu, Ugur, Terheyden, Patrick, Meier, Friedegund, Garbe, Claus, Pawelec, Graham, Weide, Benjamin, Wistuba-Hamprecht, Kilian
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6697319/
https://ncbi.nlm.nih.gov/pubmed/31419253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0221301
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