The prognostic impact of specific CD4 T-cell responses is critically dependent on the target antigen in melanoma

The melanoma-associated antigens Melan-A and NY-ESO-1 stimulate different T-cell responses in late-stage melanoma patients. Either CD4(+) or CD8(+) T-cell reactivity against NY-ESO-1 was associated with better prognosis, but for Melan-A, only CD8(+) but not CD4(+) T-cell responses were associated wi...

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Bibliographische Detailangaben
Veröffentlicht in:Oncoimmunology
Hauptverfasser: Zelba, Henning, Weide, Benjamin, Martens, Alexander, Bailur, Jithendra Kini, Garbe, Claus, Pawelec, Graham
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4431484/
https://ncbi.nlm.nih.gov/pubmed/26097797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/21624011.2014.955683
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