Monocytic myeloid-derived suppressor cells in advanced melanoma patients: Indirect impact on prognosis through inhibition of tumor-specific T-cell responses?

The percentage of circulating CD14(+)CD11b(+)HLA-DR(−/low) myeloid-derived suppressor cells (MDSCs) inversely correlates with survival among advanced melanoma patients. High levels of MDSCs are associated with the absence of T lymphocytes specific for melanoma-derived antigens, implying a causal and...

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Bibliographic Details
Main Authors: Martens, Alexander, Zelba, Henning, Garbe, Claus, Pawelec, Graham, Weide, Benjamin
Format: Artigo
Language:Inglês
Published: Landes Bioscience 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4008451/
https://ncbi.nlm.nih.gov/pubmed/24800171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.27845
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