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Comprehensive Analysis of Titin Protein Isoform and Alternative Splicing in Normal and Mutant Rats
Titin is a giant protein with multiple functions in cardiac and skeletal muscles. Rat cardiac titin undergoes developmental isoform transition from the neonatal 3.7 MDa N2BA isoform to primarily the adult 2.97 MDa N2B isoform. An autosomal dominant mutation dramatically altered this transformation....
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| Publié dans: | J Cell Biochem |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6696936/ https://ncbi.nlm.nih.gov/pubmed/22105831 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.23459 |
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