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Comprehensive Analysis of Titin Protein Isoform and Alternative Splicing in Normal and Mutant Rats

Titin is a giant protein with multiple functions in cardiac and skeletal muscles. Rat cardiac titin undergoes developmental isoform transition from the neonatal 3.7 MDa N2BA isoform to primarily the adult 2.97 MDa N2B isoform. An autosomal dominant mutation dramatically altered this transformation....

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Bibliografiske detaljer
Udgivet i:J Cell Biochem
Main Authors: Li, Shijun, Guo, Wei, Schmitt, Benjamin M., Greaser, Marion L.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6696936/
https://ncbi.nlm.nih.gov/pubmed/22105831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.23459
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