Mutation that Dramatically Alters Rat Titin Isoform Expression and Cardiomyocyte Passive Tension

Titin is a very large alternatively spliced protein that performs multiple functions in heart and skeletal muscle. A rat strain is described with an autosomal dominant mutation that alters the isoform expression of titin. While wild type animals go through a developmental program where the 3.0 MDalt...

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Detalhes bibliográficos
Main Authors: Greaser, Marion L., Warren, Chad M., Esbona, Karla, Guo, Wei, Duan, Yingli, Parrish, Amanda M., Krzesinski, Paul R., Norman, Holly S., Dunning, Sandra, Fitzsimons, Daniel P., Moss, Richard L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2501117/
https://ncbi.nlm.nih.gov/pubmed/18387630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2008.02.272
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