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Interrogating the Essential Bacterial Cell Division Protein FtsQ with Fragments Using Target Immobilized NMR Screening (TINS)

The divisome is a large protein complex that regulates bacterial cell division and therefore represents an attractive target for novel antibacterial drugs. In this study, we report on the ligandability of FtsQ, which is considered a key component of the divisome. For this, the soluble periplasmic do...

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Dades bibliogràfiques
Publicat a:Int J Mol Sci
Autors principals: Glas, Marjolein, AB, Eiso, Hollander, Johan, Siegal, Gregg, Luirink, Joen, de Esch, Iwan
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6695665/
https://ncbi.nlm.nih.gov/pubmed/31357624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20153684
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