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Interrogating the Essential Bacterial Cell Division Protein FtsQ with Fragments Using Target Immobilized NMR Screening (TINS)

The divisome is a large protein complex that regulates bacterial cell division and therefore represents an attractive target for novel antibacterial drugs. In this study, we report on the ligandability of FtsQ, which is considered a key component of the divisome. For this, the soluble periplasmic do...

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書目詳細資料
發表在:Int J Mol Sci
Main Authors: Glas, Marjolein, AB, Eiso, Hollander, Johan, Siegal, Gregg, Luirink, Joen, de Esch, Iwan
格式: Artigo
語言:Inglês
出版: MDPI 2019
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6695665/
https://ncbi.nlm.nih.gov/pubmed/31357624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20153684
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