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Interrogating the Essential Bacterial Cell Division Protein FtsQ with Fragments Using Target Immobilized NMR Screening (TINS)

The divisome is a large protein complex that regulates bacterial cell division and therefore represents an attractive target for novel antibacterial drugs. In this study, we report on the ligandability of FtsQ, which is considered a key component of the divisome. For this, the soluble periplasmic do...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Glas, Marjolein, AB, Eiso, Hollander, Johan, Siegal, Gregg, Luirink, Joen, de Esch, Iwan
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6695665/
https://ncbi.nlm.nih.gov/pubmed/31357624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20153684
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