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The Development of Tetrazole Derivatives as Protein Arginine Methyltransferase I (PRMT I) Inhibitors

Protein arginine methyltransferase 1 (PRMT1) can catalyze protein arginine methylation by transferring the methyl group from S-adenosyl-L-methionine (SAM) to the guanidyl nitrogen atom of protein arginine, which influences a variety of biological processes. The dysregulation of PRMT1 is involved in...

詳細記述

保存先:
書誌詳細
出版年:Int J Mol Sci
主要な著者: Sun, Yutong, Wang, Zhe, Yang, Hao, Zhu, Xuanli, Wu, Han, Ma, Lu, Xu, Fang, Hong, Wei, Wang, Hao
フォーマット: Artigo
言語:Inglês
出版事項: MDPI 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6695598/
https://ncbi.nlm.nih.gov/pubmed/31390828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20153840
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