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Acid sphingomyelinase plays a critical role in LPS- and cytokine-induced tissue factor procoagulant activity

Tissue factor (TF) is a cofactor for factor VIIa and the primary cellular initiator of coagulation. Typically, most TF on cell surfaces exists in a cryptic coagulant-inactive state but are transformed to a procoagulant form (decryption) following cell activation. Our recent studies in cell model sys...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Wang, Jue, Pendurthi, Usha R., Rao, L. Vijaya Mohan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6695563/
https://ncbi.nlm.nih.gov/pubmed/31262782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2019001400
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