SARS-CoV-2 infection induces the activation of tissue factor–mediated coagulation via activation of acid sphingomyelinase

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is associated with the hypercoagulable state. Tissue factor (TF) is the primary cellular initiator of coagulation. Most of the TF expressed on cell surfaces remains cryptic. Sphingomyelin (SM) is responsible for maintaining TF in...

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Dades bibliogràfiques
Publicat a:Blood
Autors principals: Wang, Jue, Pendurthi, Usha R., Yi, Guohua, Rao, L. Vijaya Mohan
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2021
Matèries:
Brief Report
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8172270/
https://ncbi.nlm.nih.gov/pubmed/34075401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2021010685
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