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Design of high-order antibiotic combinations against M. tuberculosis by ranking and exclusion

Combinations of more than two drugs are routinely used for the treatment of pathogens and tumors. High-order combinations may be chosen due to their non-overlapping resistance mechanisms or for favorable drug interactions. Synergistic/antagonistic interactions occur when the combination has a higher...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Yilancioglu, Kaan, Cokol, Murat
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6695482/
https://ncbi.nlm.nih.gov/pubmed/31417151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-48410-y
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