Combined Blockade of Smad3 and JNK Pathways Ameliorates Progressive Fibrosis in Folic Acid Nephropathy

Acute kidney injury leading to chronic kidney disease through tubulointerstitial fibrosis is a major challenge in nephropathy. Several signaling pathways promote interstitial fibrosis; however, effective suppression of fibrosis may require blockade of more than one pathway. This study investigated w...

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Bibliografiske detaljer
Udgivet i:Front Pharmacol
Main Authors: Jiang, Mengjie, Fan, Jinjin, Qu, Xinli, Li, Songhui, Nilsson, Susan K., Sun, Yu Bo Yang, Chen, Yaping, Yu, Di, Liu, Dan, Liu, Bi-Cheng, Tang, Mingliang, Chen, Wei, Ren, Yi, Nikolic-Paterson, David J., Jiang, Xiaoyun, Li, Jinhua, Yu, Xueqing
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2019
Fag:
Pharmacology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6695473/
https://ncbi.nlm.nih.gov/pubmed/31447676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00880
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