Novel method for action potential measurements from intact cardiac monolayers with multiwell microelectrode array technology

The cardiac action potential (AP) is vital for understanding healthy and diseased cardiac biology and drug safety testing. However, techniques for high throughput cardiac AP measurements have been limited. Here, we introduce a novel technique for reliably increasing the coupling of cardiomyocyte syn...

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Pubblicato in:Sci Rep
Autori principali: Hayes, Heather B., Nicolini, Anthony M., Arrowood, Colin A., Chvatal, Stacie A., Wolfson, David W., Cho, Hee Cheol, Sullivan, Denise D., Chal, Jérome, Fermini, Bernard, Clements, Mike, Ross, James D., Millard, Daniel C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6695445/
https://ncbi.nlm.nih.gov/pubmed/31417144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-48174-5
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