Novel method for action potential measurements from intact cardiac monolayers with multiwell microelectrode array technology

The cardiac action potential (AP) is vital for understanding healthy and diseased cardiac biology and drug safety testing. However, techniques for high throughput cardiac AP measurements have been limited. Here, we introduce a novel technique for reliably increasing the coupling of cardiomyocyte syn...

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Udgivet i:Sci Rep
Main Authors: Hayes, Heather B., Nicolini, Anthony M., Arrowood, Colin A., Chvatal, Stacie A., Wolfson, David W., Cho, Hee Cheol, Sullivan, Denise D., Chal, Jérome, Fermini, Bernard, Clements, Mike, Ross, James D., Millard, Daniel C.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6695445/
https://ncbi.nlm.nih.gov/pubmed/31417144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-48174-5
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