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Characterization of Early Cortical Neural Network Development in Multiwell Microelectrode Array Plates

We examined neural network ontogeny using microelectrode array (MEA) recordings made in multiwell MEA (mwMEA) plates over the first 12 days in vitro (DIV). In primary cortical cultures, action potential spiking activity developed rapidly between DIV 5 and 12. Spiking was sporadic and unorganized at...

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Detalhes bibliográficos
Publicado no:J Biomol Screen
Main Authors: Cotterill, Ellese, Hall, Diana, Wallace, Kathleen, Mundy, William R., Eglen, Stephen J., Shafer, Timothy J.
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4904353/
https://ncbi.nlm.nih.gov/pubmed/27028607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1087057116640520
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