Characterization of Early Cortical Neural Network Development in Multiwell Microelectrode Array Plates

We examined neural network ontogeny using microelectrode array (MEA) recordings made in multiwell MEA (mwMEA) plates over the first 12 days in vitro (DIV). In primary cortical cultures, action potential spiking activity developed rapidly between DIV 5 and 12. Spiking was sporadic and unorganized at...

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Vydáno v:J Biomol Screen
Hlavní autoři: Cotterill, Ellese, Hall, Diana, Wallace, Kathleen, Mundy, William R., Eglen, Stephen J., Shafer, Timothy J.
Médium: Artigo
Jazyk:Inglês
Vydáno: SAGE Publications 2016
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4904353/
https://ncbi.nlm.nih.gov/pubmed/27028607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1087057116640520
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