Characterization of Early Cortical Neural Network Development in Multiwell Microelectrode Array Plates

We examined neural network ontogeny using microelectrode array (MEA) recordings made in multiwell MEA (mwMEA) plates over the first 12 days in vitro (DIV). In primary cortical cultures, action potential spiking activity developed rapidly between DIV 5 and 12. Spiking was sporadic and unorganized at...

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Библиографические подробности
Опубликовано в: :J Biomol Screen
Главные авторы: Cotterill, Ellese, Hall, Diana, Wallace, Kathleen, Mundy, William R., Eglen, Stephen J., Shafer, Timothy J.
Формат: Artigo
Язык:Inglês
Опубликовано: SAGE Publications 2016
Предметы:
Original Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4904353/
https://ncbi.nlm.nih.gov/pubmed/27028607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1087057116640520
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