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Effects of an Environmentally-relevant Mixture of Pyrethroid Insecticides on Spontaneous Activity in Primary Cortical Networks on Microelectrode Arrays

Pyrethroid insecticides exert their insecticidal and toxicological effects primarily by disrupting voltage-gated sodium channel (VGSC) function, resulting in altered neuronal excitability. Numerous studies of individual pyrethroids have characterized effects on mammalian VGSC function and neuronal e...

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Détails bibliographiques
Publié dans:Neurotoxicology
Auteurs principaux: Johnstone, Andrew F.M., Strickland, Jenna D., Crofton, Kevin M, Gennings, Chris, Shafer, Timothy J.
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5831128/
https://ncbi.nlm.nih.gov/pubmed/27177986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuro.2016.05.005
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