Ectopic activation of WNT signaling in human embryonal carcinoma cells and its effects in short- and long-term in vitro culture

Human embryonal carcinoma (EC) cells comprise the pluripotent stem cells of malignant non-seminomatous germ cell tumors (GCTs) and represent the malignant counterpart of embryonic stem cells (ESCs). WNT/β-catenin signaling has been implicated in regulating adult and embryonic stem cells although its...

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Vydáno v:Sci Rep
Hlavní autoři: Atlasi, Yaser, van Dorsten, Rebecca T., Sacchetti, Andrea, Joosten, Rosalie, Oosterhuis, J. Wolter, Looijenga, Leendert H. J., Fodde, Riccardo
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6695393/
https://ncbi.nlm.nih.gov/pubmed/31417131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-48396-7
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