Wnt Signaling in Ovarian Cancer Stemness, EMT, and Therapy Resistance

Ovarian cancers represent the deadliest among gynecologic malignancies and are characterized by a hierarchical structure with cancer stem cells (CSCs) endowed with self-renewal and the capacity to differentiate. The Wnt/β-catenin signaling pathway, known to regulate stemness in a broad spec...

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Bibliografiske detaljer
Main Authors: Miriam Teeuwssen, Riccardo Fodde
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2019-10-01
Serier:Journal of Clinical Medicine
Fag:
ovarian cancer
wnt signaling
cancer stem cells
tumor progression
therapy resistance
exosomes
Online adgang:https://www.mdpi.com/2077-0383/8/10/1658
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