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Hyperglycemia acts in synergy with hypoxia to maintain the pro-inflammatory phenotype of macrophages
Diabetic foot ulcers (DFUs) are characterized by a chronic inflammation state which prevents cutaneous wound healing, and DFUs eventually lead to infection and leg amputation. Macrophages located in DFUs are locked in an pro-inflammatory phenotype. In this study, the effect of hyperglycemia and hypo...
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| Pubblicato in: | PLoS One |
|---|---|
| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6695165/ https://ncbi.nlm.nih.gov/pubmed/31415598 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0220577 |
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