Identification of a Mycobacterium tuberculosis Gene That Enhances Mycobacterial Survival in Macrophages

Intracellular survival plays a central role in the pathogenesis of Mycobacterium tuberculosis. To identify M. tuberculosis genes required for intracellular survival within macrophages, an M. tuberculosis H37Rv plasmid library was constructed by using the shuttle vector pOLYG. This plasmid library wa...

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Autori principali: Wei, Jun, Dahl, John L., Moulder, James W., Roberts, Esteban A., O'Gaora, Peadar, Young, Douglas B., Friedman, Richard L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2000
Soggetti:
Genetics and Molecular Biology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC94286/
https://ncbi.nlm.nih.gov/pubmed/10629183
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