Prediction of deleterious single nucleotide polymorphisms and their effect on the sequence and structure of the human CCND1 gene

OBJECTIVE: The CCND1 gene expresses a protein, G1/S-specific cyclin, that regulates the G1/S transition in the cell cycle and also inhibits retinoblastoma (RB) proteins. Overexpression or rearrangements of this gene can result in various tumours. This study aimed to identify possible deleterious non...

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Detalhes bibliográficos
Publicado no:J Taibah Univ Med Sci
Main Authors: Yoganarasimha, Bharath, Chandramohan, Vivek, Krishna Murthy, Thirupathihalli P., Gangadharappa, Bhavya S., Siddaiah, Gowrishankar B., Hanumanthappa, Makari
Formato: Artigo
Idioma:Inglês
Publicado em: Taibah University 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6695066/
https://ncbi.nlm.nih.gov/pubmed/31435243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtumed.2016.07.009
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