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Identification of deleterious non-synonymous single nucleotide polymorphisms using sequence-derived information

BACKGROUND: As the number of non-synonymous single nucleotide polymorphisms (nsSNPs), also known as single amino acid polymorphisms (SAPs), increases rapidly, computational methods that can distinguish disease-causing SAPs from neutral SAPs are needed. Many methods have been developed to distinguish...

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Bibliografiska uppgifter
Huvudupphovsmän: Hu, Jing, Yan, Changhui
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2008
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2446391/
https://ncbi.nlm.nih.gov/pubmed/18588693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-9-297
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