Prediction of Deleterious Non-synonymous Single-Nucleotide Polymorphisms of Human Uridine Diphosphate Glucuronosyltransferase Genes

UDP glucuronosyltransferases (UGTs) are an important class of Phase II enzymes involved in the metabolism and detoxification of numerous xenobiotics including therapeutic drugs and endogenous compounds (e.g. bilirubin). To date, there are 21 human UGT genes identified, and most of them contain singl...

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Hlavní autoři: Di, Yuan Ming, Chan, Eli, Wei, Ming Qian, Liu, Jun-Ping, Zhou, Shu-Feng
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer US 2009
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2758119/
https://ncbi.nlm.nih.gov/pubmed/19572200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-009-9126-z
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