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Monoclonal Antibody 2C6 Targets a Cross-Clade Conformational Epitope in gp41 with Highly Active Antibody-Dependent Cell Cytotoxicity

Previous studies in our laboratory characterized a panel of highly mutated HIV-specific conformational epitope-targeting antibodies (Abs) from a panel of HIV-infected long-term nonprogressors (LTNPs). Despite binding HIV envelope protein and having a high number of somatic amino acid mutations, thes...

詳細記述

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書誌詳細
出版年:J Virol
主要な著者: Sojar, Hakimuddin, Baron, Sarah, Sullivan, Jonathan T., Garrett, Meghan, van Haaren, Marlies M., Hoffman, Jonathon, Overbaugh, Julie, Doranz, Benjamin J., Hicar, Mark D.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6694811/
https://ncbi.nlm.nih.gov/pubmed/31217246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00772-19
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