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Design and Intracellular Activity of a Human Single-Chain Antibody to Human Immunodeficiency Virus Type 1 Conserved gp41 Epitope

A human lymphoid cell line (F172-D8) excreting a human immunodeficiency virus type 1 (HIV-1) anti-gp41 monoclonal antibody was used to construct a plasmid containing the cDNA of the single-chain variable fragment (scFvD8) corresponding to this antibody. A stable human osteosarcoma cell line was obta...

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Main Authors: Legastelois, Isabelle, Desgranges, Claude
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2000
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC112060/
https://ncbi.nlm.nih.gov/pubmed/10823880
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