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Induction of apoptosis and modulation of homologous recombination DNA repair pathway in prostate cancer cells by the combination of AZD2461 and valproic acid
Cancer therapies using defects in homologous recombination (HR) DNA repair pathway of tumor cells are not yet approved to be applicable in patients with malignancies other than BRCA1/2-mutated tumors. This study was designed to determine the efficacy of combination therapy of a histone deacetylase i...
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| Publié dans: | EXCLI J |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Leibniz Research Centre for Working Environment and Human Factors
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6694702/ https://ncbi.nlm.nih.gov/pubmed/31423128 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.17179/excli2019-1098 |
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