Induction of apoptosis and modulation of homologous recombination DNA repair pathway in prostate cancer cells by the combination of AZD2461 and valproic acid

Cancer therapies using defects in homologous recombination (HR) DNA repair pathway of tumor cells are not yet approved to be applicable in patients with malignancies other than BRCA1/2-mutated tumors. This study was designed to determine the efficacy of combination therapy of a histone deacetylase i...

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Detalhes bibliográficos
Publicado no:EXCLI J
Main Authors: Sargazi, Saman, Saravani, Ramin, Zavar Reza, Javad, Jaliani, Hossein Zarei, Mirinejad, Shekoufeh, Rezaei, Zohreh, Zarei, Sadegh
Formato: Artigo
Idioma:Inglês
Publicado em: Leibniz Research Centre for Working Environment and Human Factors 2019
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6694702/
https://ncbi.nlm.nih.gov/pubmed/31423128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.17179/excli2019-1098
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