Induction of apoptosis and modulation of homologous recombination DNA repair pathway in prostate cancer cells by the combination of AZD2461 and valproic acid

Cancer therapies using defects in homologous recombination (HR) DNA repair pathway of tumor cells are not yet approved to be applicable in patients with malignancies other than BRCA1/2-mutated tumors. This study was designed to determine the efficacy of combination therapy of a histone deacetylase i...

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Detalles Bibliográficos
Publicado en:EXCLI J
Autores principales: Sargazi, Saman, Saravani, Ramin, Zavar Reza, Javad, Jaliani, Hossein Zarei, Mirinejad, Shekoufeh, Rezaei, Zohreh, Zarei, Sadegh
Formato: Artigo
Lenguaje:Inglês
Publicado: Leibniz Research Centre for Working Environment and Human Factors 2019
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6694702/
https://ncbi.nlm.nih.gov/pubmed/31423128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.17179/excli2019-1098
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